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The study showed that subjects with TS, unlike those of a similar age without the condition, were least able to modulate the hyperactivity in the brain.Professor Jackson said: "If there is a relationship between this cortical excitability or hyperactivity and tics then this is really important as it means that there may be something that we might be able to do to help children with TS to better control these unwanted movements." Further research by the team has involved the use of a similar type of brain stimulation called transcranial direct current stimulation (TDCS) to study the brains of children with TS.

"It can be applied at home while the child is watching TV or eating their cornflakes so it would reduce the amount of school they would miss and potentially we can use the TDCS to both control the tics and make that control more effective and longer lasting." As part of her work Amelia Draper is also using MRI scanning technology to examine the potential relationship between cortical excitability and a brain chemical that appears to be strongly linked to neuronal excitability in TS.The neurological condition TS affects around one child in every 100 and usually starts during early childhood.Scientists believe that the tics that affect children with TS are caused by faulty wiring in the brain that leads to hyper excitability in the brain regions controlling motor function.Professor Stephen Jackson, in the University's School of Psychology, said: "This new study is very important as it indicates that motor and vocal tics in children may be controlled by brain changes that alter the excitability of brain cells ahead of voluntary movements.You can think of this as a bit like turning the volume down on an over-loud motor system.

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